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韩明勇
韩明勇
教授 博士生导师 入选全球高被引科学家(Highly Cited Scientists)
邮箱:han_mingyong@tju.edu.cn; my-han@imre.a-star.edu.sg.
研究方向:多维功能纳米结构及生物, 光电和能源应用 化学生物学,合成生物学及分子水平机制

 

个人简介

韩明勇博士,天津大学教授,博士生导师,国家特聘专家和国家高层次人才,教育部合成生物学前沿科学中心 PI,新加坡材料研究院研究员和新加坡国立大学生物医学工程教授,入选英国皇家化学学会会士和全球高被引科学家, 获新加坡国立大学和生物医学协会奖。他的科研集中在化学合成功能纳米材料和多维功能纳米结构及其生物, 光电和能源应用,其中生物医学应用包括编码、杂化、成像、检测、诊断和治疗。同时,发展化学生物学和合成生物学新途径,利用活生物体合成新的高性能生物材料并取得生物功能的调控等。

他的学术生涯从中科院化学所开始,先后师从李铁津, 朱道本, 白春礼和聂书明老师。近年来,主持过四十余项政府和公司支持的研究项目包括多项国际合作项目,做出了一系列国际上领先的开创性工作,其研究成果已在国际知名刊物发表论文 220 多篇(他引20,000余次, H指数70, Advanced Materials, Angewandte Chemie, Chemical Society Reviews, Journal of the American Chemical Society, Nature Biotechnology, Nature Protocols, Nano Letters等五十余篇影响因子大于10的文章),受到国际同行的高度认可,关注和评价,并获得国际知名媒介进行了广泛报道 300余次,其中包括《自然》《自然新闻》《自然化学》《自然生物科技》《科学》《科学新闻》《科学时报》《纽约时报》《BBC新闻》《联合早报》、《海峡时报》、台湾中天电视等等。拥有国际及各国专利申请百余项,生成了多种高科技产品,已催生了多家原创高科技公司。

 

RESEARCH HIGHLIGHTS

-        Research news from more than three hundred professional magazines or organizations

-        Scientific publications: Nature, Nature News, Nature Biotechnology, Nature Genetics, Nature Chemistry, Nature Asia Materials, Science News, Science Times, Science et Avenir, Scientific American, New Scientists, Chemical & Engineering News, Chemistry World, Materials Today, tce today (UK), Biocentury Publishing, Biophotonics International, IEEE Spectrum, Photonics Spectra Magazine, Sensor Technology Alert, Laser Focus World, Institute of Physics Publishing, PhysOrg.com (USA), Ananova, Augusta Chronicle, Analytical Chemistry, Wiley, ACS, ACS Heart Cut and Patent Watch, etc.

-        General publications: The New York Times, International Herald Tribune (global edition of the New York Times), Australian Geographics (Australia), BBC News (UK), Wissenchaft aktuell (Germany), Science et Vie Junior (France), IO Donna (Italy), KopalniaWiedzy.pl (Poland),中天電視-CtiTV.com (Taiwan), The Technical Review from Netherlands, The Whitaker Foundation for Biomedical Engineering, Indiana Daily Insight, John & Wiley Publisher R&D Inside, Hul-MolGen News, Germany Genesis, Future Materials (international textile industry newsletter), FuturoTextiles (touring exhibition combining sciences, technology, textile and art), etc.

-        Local media: The Straits Times (Singapore Press Holding)Strait Times, Lianhe Zhaobao, A-Star Research Highlights, NUS FoS Newsletter, University Research Highlight, Channel 8, Channel 5, Channel News Asia, etc.

 

SELECTED PUBLICATIONS

1.

Guijian Guan, Mingyong Han, Functionalized hybridization of 2D nanomaterials, Advanced Science, https://doi.org/10.1002/advs.201901837, 2019.

2.

Guangmei Han, Jun Zhao, Ruilong Zhang, Xiaohe Tian, Zhengjie Liu, Aidong Wang, Renyong Liu, Bianhua Liu, Ming-Yong Han*, Xiaohu Gao, Zhongping Zhang, Membrane-penetrating carbon quantum dots for imaging nucleic acid structures in live organisms, Angewandte Chemie, 58(21),7087-7091, 2019.

3.

 

Cui Ma-Lin, Chen Yi-Song, Xie Qing-Fan, Yang Da-Peng, Han Ming-Yong, Synthesis, properties and applications of noble metal iridium nanomaterials, Coordination Chemistry Reviews, 2019, 387(15), 450–462.

4.

 

Guijian Guan, Mingda Wu, Mingyong Han, Stimuli-responsive hybridized nanostructures, Advanced Functional Materials, Doi.org/10.1002/adfm.201903439, 1903439, 2019.

5.

Zhongping Zhang, Qingsong Mei; Bianhua Liu; Ming-Yong Han, Graphene oxide: from tunable structures to diverse luminescence behaviors, Advanced Science,

DOI: 10.1002/advs.201900855, 2019.

6.

 

Liu Zhengjie, Zhao Jun, Zhang Reilong, Han Guangmei, Zhang Cheng, Liu Bianhua, Zhang Zhongping, Han, Ming-Yong, Gao Xiaohu, Cross-platform cancer molecular phenotyping using telomerase-specific SNAs, ACS Nano. 12(4):3629-3637, doi: 10.1021/acsnano.8b00743, 2018.

7.

 

Guijian Guan, Jing Xia, Shuhua Liu, Yuan Cheng, Shiqiang Bai, Si Yin Tee, Yong-Wei Zhang, Ming-Yong Han, Electrostatic-Driven Exfoliation and Hybridization of Two Dimensional Nanomaterials" Advanced Materials, 29(32), 1700326, doi: 10.1002/adma.201700326, 2017.

8.

Ice Tee, Han Ming-Yong, Recent Progress in Energy-driven Water Splitting, Advanced Science (invited), 4(5), 1600337, 2017.

9.

Shuhua Liu, Xiangyang Liu, Ming-Yong Han, Controlled Modulation of Surface Coating and Surface Charging on Quantum Dots with Negatively Charged Gelatin for Substantial Enhancement and Reversible Switching in Photoluminescence, Advanced Functional Materials, 26 (48), 8991–8998, 2016.

10.

Ruchuan Liu, Qinqiu Deng, Zhen Yang, Daiwen Yang, Ming-Yong Han, Xiang Yang Liu, Nano Fishnet Structure Making Silk Fibers Tougher, Advanced Functional Materials, 26:30, 5534–5541, 2016.

11.

Duc-Viet Nguyen, Shengwei Jiang, Chengyong He, Zhongning Lin, Naibo Lin, Anh-Tuan Nguyen, Lifeng Kang, Ming-Yong Han, Xiang Yang Liu, Elevating Biomedical Performance of ZnO/SiO2@Amorphous Calcium Phosphate - Bioinspiration Making Possible from the “Impossible”, Advanced Functional Materials, 26:38, 6921–6929, 2016. 

12

Choon Peng Teng, Khin Yin Win, Tielin Zhou b, Enyi Ye, Michelle Low, Lianhui Zhang, Ming-Yong Han, Effective Targeted Photothermal Ablation of Multidrug Resistant Bacteria and Their Biofilms with NIR-absorbing Gold Nanocrosses, Advanced Healthcare Materials, 5:16, 2122–30, 2016.

13.

 

Ruilong Zhang, Jun Zhao, Guangmei Han, Zhengjie Liu, Cui Liu, Bianhua Liu, Changlong Jiang, Renyong Liu, Tingting Zhao, Ming-Yong Han, Zhongping Zhang, Real-Time Discrimination and Versatile Profiling of Spontaneous ROS in Living Organisms with a Single Fluorescent Probe, Journal of the American Chemical Society, 138: 11, 3769–3778, 2016.

14.

 

Michelle D. Regulacio, Ming-Yong Han, Multinary I-III-VI2 and I-II-IV-VI4 Semiconductor Nanostructures for Photocatalytic Applications, Account of Chemical Research 49, 511–519, 2016.

15.

 

Bowen Zhu, Hong Wang, Wan Ru Leow, Yurong Cai, Xian Jun Loh, Ming-Yong Han, Xiaodong Chen, Silk Fibroin for Flexible Electronic Devices, Advanced Materials, 28:22, 4250–4265, 2016.

16.

 

Cheng Zhang, Liang Yang, Jun Zhao, Bianhua Liu, Ming-Yong Han, Zhongping Zhang, Single White-light Upconversion Nanostructure towards Laser Power-modulated Multicolor Display, Angewandte Chemie International Edition, 54, 11531–11535, 2015.

17.

Guijian Guan, Shuangyuan Zhang, Shuhua Liu, Yongqing Cai, Michelle Low, Choon Peng Teng, In Yee Phang, Yuan Cheng, Koh Leng Duei, Bharathi Madurai Srinivasan, Yuangang Zheng, Yong-Wei Zhang, Ming-Yong Han, Protein Induces Layer-by-Layer Exfoliation of Transition Metal Dichalcogenides, Journal of the American Chemical Society, 137 (19), 6152–6155, 2015.

18.

Enyi Ye, Michelle D. Regulacio, Shuang-Yuan Zhang, Xian Jun Loh, Ming-Yong Han, Anisotropically Branched Metal Nanostructures, Chemical Society Review, 44, 6001 - 6017, 2015.

19.

Shan Jiang, Thammanoon Sreethawong, Serina Siew Chen Lee, Michelle Bee Jin Low, Khin Yin Win, Agata Maria Brzozowska, Serena Lay-Ming Teo, G. Julius Vancso, Dominik Jańczewski, Ming-Yong Han, Fabrication of Copper Nanowire Films and Their Incorporation into Polymer Matrices for Antibacterial and Marine Antifouling Applications, Advanced Materials Interface, 2(3), DOI: 10.1002/admi.201400483, 2015

20.

Leng-Duei Koh, Yuan Cheng, Choon-Peng Teng, Yin-Win Khin, Xian-Jun Loh, Si-Yin Tee1, Bee-Jin Low, Enyi Ye, Hai-Dong Yu, Yong-Wei Zhang, Ming-Yong Han, Structures, Mechanical Properties and Applications of Silk Fibroin Materials, Progress in Polymer Science, 46, 86–110, 2015.

21.

Khin Yin Win, Choon Peng Teng, Khine Yi Mya, Chee Chuan Yeo, Michelle Low, Chaobin He, Mingyong Han, Star-shaped POSS-PCL-PU as Biomaterials for Tissue Engineering Application, NPG Asia Materials, 6, e142, 2014.

22.

Liang Yang, Ruilong Zhang, Bianhua Liu, Jianping Wang, Suhua Wang, Ming-Yong Han, Zhongping Zhang, π-Conjugated Carbon Radicals at Graphene Oxide to Initiate the Ultrastrong Chemiluminensence, Angewandte Chemie International Edition, 53(38), 10109–10113, 2014.

23.

Guijian Guan, Shuhua Liu, Yongqing Cai, Michelle Low, M. S. Bharathi1, Shuangyuan Zhang, Shiqiang Bai, Yong-Wei Zhang, Ming-Yong Han, Destabilization of Gold Clusters for Controlled Nanosynthesis: From Clusters to Polyhedra, Advanced Materials 26(21), 3427–3432, 2014.

24.

Shuangyuan Zhang, Michelle R. Regulacio, Ming-Yong Han, Self-assembly of Colloidal One-dimensional Nanocrystals, Chemical Society Reviews, 43 (7), 2301–2323, 2014.

25.

Haidong Yu, Michelle D. Regulacio, Enyi Ye, Ming-Yong Han, Chemical Route to Top-down Nanofabrication, Chemical Society Reviews, 42 (14), 6006–6018, 2013.

26.

Hang Sun, Jiating He, Jiangyan Wang, Shuangyuan Zhang, Cuicui Liu, Thirumany Sritharan, Subodh Mhaisalkar, Mingyong Han, Dan Wang, Hongyu Chen, Investigating the Multiple Roles of Polyvinylpyrrolidone for a General Methodology of Oxide Encapsulation, Journal of the American Chemical Society, 135 (24), 9099–9110, 2013.

27.

Zhi Wei Seh, Shuhua Liu, Michelle Low, Adnen Mlayah, Ming-Yong Han, Janus Au-TiO2 Photocatalysts with Strong Localization of Plasmonic Near-Fields for Efficient Visible-Light Hydrogen Generation, Advanced Materials, 24(17), 2310–2314, 2012.

28.

Natalia C. Tansil1, Leng Duei Koh, Ming-Yong Han, Functional Silk: Colored and Luminescent, Advanced Materials, 24(11), 1388–1397, 2012. (Front Inside Cover)

29.

Shuang-Yuan Zhang, Enyi Ye, Shuhua Liu, Lim, Suo Hon Lim, Si Yin Tee, Zhili Dong, Ming-Yong Han, Temperature and Chemical Bonding-Directed Self-Assembly of Cobalt Phosphide Nanowires in Reaction Solutions into Vertical and Horizontal Alignments, Advanced Materials, 24(32), 4369–4375, 2012.

30.

Enyi Ye, Khin Yin Win, Hui Ru Tan, Ming Lin, Choon Peng Teng, Adnen Mlayah, Ming-Yong Han, Plasmonic Gold Nanocrosses with Multidirectional Excitation and Strong Photothermal Effect, Journal of the American Chemical Society, 133(22), 8506–8509,  2011.

31.

Zhi Wei Seh, Shuhua Liu, Shuang-Yuan Zhang, M. S. Bharathi, H. Ramanarayan, Michelle Low, Kwok Wei Shah, Yong-Wei Zhang, Ming-Yong Han, Anisotropic Growth of Titania onto Various Gold Nanostructures: Synthesis, Theoretical Understanding, Optimization for Catalysis, Angewandte Chemie International Edition, 50(43), 10140–10143, 2011.

32.

Natalia C. Tansil, Yang Li, Leng Duei Koh, Xiang Yang Liu, Ming-Yong Han, The Use of Molecular Fluorescent Markers to Monitor Absorption and Distribution of Xenobiotics in a Silkworm Model, Biomaterials, 32(36), 9576–9583, 2011.

33.

Enyi Ye, Khin Yin Win, Hui Ru Tan, Ming Lin, Choon Peng Teng, Adnen Mlayah, Ming-Yong Han, Plasmonic Gold Nanocrosses with Multi-directional Excitation and Strong Photothermal Effect, Journal of the American Chemical Society, 133, 8506–8509, 2011.

34.

Dominik Jańczewski, Nikodem Tomczak, Ming-Yong Han, G. Julius Vancso, Facile Synthesis of Functionalized Amphiphilic Polymers as Versatile Functional Coating Platform for Quantum Dots, Nature Protocols, 6, 1546, 2011.

35.

Natalia C. Tansil, Yang Li, Choon Peng Teng, Shuangyuan Zhang, Khin Yin Win, Xing Chen, Xiang Yang Liu, Ming-Yong Han, Intrinsically Colored and Luminescent Silk, Advanced Materials, 23(12), 1463–1466, 2011.  

36.

Sudhiranjan Tripathy, Renaud Marty, Vivian Kaixin Lin, Siew Lang Teo, Enyi Ye, Arnaud Arbouet, Lucien Saviot, Christian Girard, Ming-Yong Han, Adnen Mlayah, Acousto-Plasmonic and Surface-Enhanced Raman Scattering Properties of Coupled Gold Nanospheres/Nanodisk Trimers, Nano Letters, 11(2), 431–437, 2011.

37.

Michelle D. Regulacio, Chen Ye, Suo Hon Lim, Michel Bosman, Lakshminarayana Polavarapu, Wei Ling Koh, Jie Zhang, Qing-Hua Xu, Ming-Yong Han, One-Pot Synthesis of Cu1.94S-CdS and Cu1.94S-ZnxCd1-xS Nanodisk Heterostructures. Journal of the American Chemical Society, 133(7), 2052–2055, 2011.

38.

Hai-Dong Yu, Dapeng Yang, Deshen Wang, Ming-Yong Han, Top-Down Fabrication of Calcite Nanoshoot Arrays by Crystal Dissolution, Advanced Materials, 22(29), 3181–3184, 2010.

39.

Michelle D. Regulacio, Ming-Yong Han, Composition-Tunable Alloyed Semiconductor Nanocrystals, Accounts of Chemical Research, 43(5), 621–630, 2010.

40.

Suhua Wang, Ming- Yong Han, Dejian Huang, Nitric Oxide Switches on the Photoluminescence of Molecularly Engineered Quantum Dots, Journal of the American Chemical Society, 131(33), 11692–11695, 2009.  

41.

Dominik Jańczewski, Nikodem Tomczak, Ming-Yong Han, G. Julius Vancso, Designer Polymer-Quantum Dot Architectures, Progress in Polymer Science, 34 (5), 393-430, 2009 (The top 25 hottest articles published in Science Direct for April-June, 2009).

42.

Denis Dorokhin, Nikodem Tomczak, Ming-Yong Han, David N. Reinhoudt, Aldrik H. Velders, Vancso, G. Julius, Reversible Phase Transfer of (CdSe/ZnS) Quantum Dots between Organic and Aqueous Solutions, ACS Nano, 3(3), 661–667, 2009. (Top 20 most downloaded articles)                        

43.

H. D. Yu, D. S. Wang, M. Y. Han, Perpendicular Branching in Crystal Growth of 3D Architecture-Tuned Cadmium Oxide Arrays: From Oriented Tripods to Faceted Crystals, Advanced Materials, 20(12), 2276–2279, 2008.

44.

S. H. Liu, Y. Wong, Y. Wang, D. Wang, M. Y. Han, Controlled Release and Absorption Resonance of Fluorescent Silica-coated Platinum Nanoparticles, Advanced Functional Materials, 17 (16), 3147–3152, 2007.

45.

H. D. Yu, D. S. Wang, M. Y. Han, Top-down Solid-Phase Fabrication of Nanoporous Cadmium Oxide Architectures, Journal of the American Chemical Society, 129(8), 2333–2337, 2007.

46.

S. H. Liu, Z. H. Zhang, M. Y. Han, Nanosized Gold-Loaded Gelatin/Silica Nanocapsules, Advanced Materials, 17(15), 1862–1866, 2005.

47.

F. K. Wang, M.Y. Han, K. Y. Mya, Y. B. Wang, Y. H. Lai, Aggregation-Driven Growth of Size-Tunable Organic Nanoparticles Using Electronically-Altered Conjugated Polymers, Journal of the American Chemical Society, 127(29), 10350-10355, 2005 (highlighted by the American Chemical Society Heart Cut and Patent Watch on August 29, 2005).

48.

Z. H. Zhang, X. H. Zhong, S. H. Liu, D. F. Li, M. Y. Han, Aminolysis Route to Monodisperse Titania Nanorods with Tunable Aspect Ratio, Angewandte Chemie International Edition, 44(22), 3466–3470, 2005.

49.

S. H. Liu, Z. H. Zhang, M. Y. Han, Gram-scale Synthesis and Bio-functionalization of Silica-coated Silver Nanoparticles for Fast Colorimetric DNA Detection, Analytical Chemistry, 77(8), 2595–2600, 2005.

50.

S. H. Liu, M. Y. Han, Synthesis, Functionalization and Bioconjugation of Monodisperse Silica-Coated Gold Nanoparticles as Robust Nanoprobes, Advanced Functional Materials, 15(6), 961-967, 2005.

51.

H. D. Yu, Z. P. Zhang, M. Y. Han, X. T. Hao, F. R. Zhu, A General Low-Temperature Route for Large-Scale Fabrication of Highly Oriented ZnO Nanorod/Nanotube Arrays, Journal of the American Chemical Society, 127(8), 2378–2379, 2005 (Featured at Materials Today).

52.

Z. P. Zhang, H. P. Sun, X. Q. Shao, D. F. Li, H. D. Yu, M. Y. Han, Three-dimensionally Oriented Aggregation of a Few Hundred Nanoparticles into Monocrystalline Architectures, Advanced Materials, 17(1), 42–47, 2005 (a breaking paper in Thomson).

53.

X. H. Zhong, Y. Feng, W. Knoll, M. Y. Han, Alloyed ZnCdS Nanocrystals with Highly Narrow Luminescence Spectral Width, Journal of the American Chemical Society, 125(44), 13559–13563, 2003. (>500 citations)

54.

X. H. Zhong, M. Y. Han, Z. L. Dong, T. White, W. Knoll, Composition-tunable ZnCdSe Nanocrystals with High Luminescence and Stability, Journal of the American Chemical Society, 125(28), 8589–8594, 2003.

55.

W. C. W. Chan, D. J. Maxwell, X. H. Gao, R. E. Bailey, M. Y. Han, S. M. Nie, Luminescent Quantum Dots for Multiplexed Biological Detection and Imaging, Current Opinion in Biotechnology, 13(1), 40–46, 2002 (featured on the cover of this issue of Current Opinion in Biotechnology with 2000 citations).

56.

M. Y. Han, X. H. Gao, J. Z. Su, S. M. Nie, Quantum Dot-tagged Microbeads for Multiplexed Optical Coding of Biomolecules, Nature Biotechnology, 19(7), 631–635, 2001 (featured on the cover of this issue Nature Biotechnology with over 3000 citations and over 70 seventy research news).

 

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